Anti-Trastuzumab Affimer® Reagent – 6xHis tag, Cystein

Highly specific Affimer® reagent against the humanised drug Trastuzumab (Herceptin).

Product Data Sheet
General
Name
Anti-Trastuzumab Affimer Reagent – 6xHis tag, Cysteine
Catalogue Code
AVA00106
Overview
Clone ID
386_737_B3
Tested Applications
ELISA
Tags
6X His, Cys
Conjugate
Unconjugated
Properties
Form
Liquid
Storage Instructions
Store at 4oC for up to 6 months. For longer term storage, it is recommended to store at -20oC in single use aliquots
Buffer
100 mM Sodium Phosphate, 150 mM Sodium Chloride, 0.02% Sodium Azide, pH 6.5
Purity
>95%
Purification Method
IMAC-SEC
Clonality
Monoclonal
Target
Target
Trastuzumab (Herceptin)
Target Function
Anti-trastuzumab Affimer binders show excellent sensitivity to the therapeutic antibody target comparable to the natural ligand, HER2. Capture ELISA data using anti-trastuzumab Affimer reagents passively adsorbed onto ELISA plate showed detection of the trastuzumab antibody target over the clinically relevant concentration range 30-1600 ng/mL, performing in line with the natural HER2 ligand, to a lower concentration of 30 ng/mL.
Species Reactivity
Human
Research Area
Toolkit