Published Papers
- Selection and characterisation of Affimers specific for CEA recognition
- Isolation of Artificial Binding Proteins (Affimer Reagents) for Use in Molecular and Cellular Biology
- Selective Affimers Recognise the BCL?2 Family Proteins BCL?xL and MCL?1?through Noncanonical Structural Motifs
- Characterization and applications of a Crimean-Congo hemorrhagic fever virus nucleoprotein-specific Affimer: Inhibitory effects in viral replication and development of colorimetric diagnostic tests
- Affimers as an alternative to antibodies for protein biomarker enrichment
- Fibrinogen interaction with complement C3: a potential therapeutic target to reduce thrombosis risk
- RAS-inhibiting biologics identify and probe druggable pockets including an SII-?3 allosteric site
- Affimer-enzyme-inhibitor switch sensor for rapid wash-free assays of multimeric proteins
- Affimers as anti-idiotypic affinity reagents for pharmacokinetic analysis of biotherapeutics
- Selective Affimers Recognize BCL-2 Family Proteins Through Non-Canonical Structural Motifs
- Affimer reagents as tools in diagnosing plant virus diseases
- Visualizing ubiquitination in mammalian cells
- Toxin Neutralization Using Alternative Binding Proteins
- Affimer proteins as a tool to modulate fibrinolysis, stabilize the blood clot and reduce bleeding complications
- A fibrin biofilm covers blood clots and protects from microbial invasion
- Affimers as an Alternative to Antibodies in an Affinity LC–MS Assay for Quantification of the Soluble Receptor of Advanced Glycation End-Products (sRAGE) in Human Serum
- Site?Specific Labeling of Affimers for DNA?PAINT Microscopy
- Affimer proteins for F-actin: novel affinity reagents that label F-actin in live and fixed cells
- Affimer Proteins: Theranostics of the Future?
- Proteomic profiling of VCP substrates links VCP to K6?linked ubiquitylation and c?Myc function
- Sensitive and selective Affimer-functionalised interdigitated electrode-based capacitive biosensor for Her4 protein tumour biomarker detection
- Non-immunoglobulin scaffold proteins: Precision tools for studying protein-protein interactions in cancer
- Affimer proteins inhibit immune complex binding to Fc?RIIIa with high specificity through competitive and allosteric modes of action
- Isolation of isoform-specific binding proteins (Affimers) by phage display using negative selection
- Generation of specific inhibitors of SUMO-1- and SUMO-2/3-mediated protein-protein interactions using Affimer (Adhiron) technology
- Mechanism and regulation of the Lys6-selective deubiquitinase USP30
- Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling
- Development of an Affimerantibody combined immunological diagnosis kit for glypican-3
- Alternative reagents to antibodies in imaging applications
- Affimer proteins are versatile and renewable affinity reagents
- Quantum Dots Wang et al 2017 ACS materials and interfaces
- Antibody Mimetics for the Detection of Small Organic Compounds Using a Quartz Crystal Microbalance
- Interfacing native and non-native peptides: using Affimers to recognise ?-helix mimicking foldamers
- Comparison of the specificity and affinity of surface immobilised Affimer binders using the quartz crystal microbalance
- The future of protein scaffolds as affinity reagents for purification
- Non-antibody protein-based biosensors.
- Label-free electrochemical impedance biosensor to detect human interleukin-8 in serum with sub-pg/ml sensitivity
- The use of a neutral peptide aptamer scaffold to anchor BH3 peptides constitutes a viable approach to studying their function.
- Phage display selected magnetite interacting Adhirons for shape controlled nanoparticle synthesis
- Exploration of the HIF-1?/p300 interface using peptide and Adhiron phage display technologies
- Trivalent Gd-DOTA reagents for modification of proteins
- Non-immunoglobulin scaffolds: a focus on their targets
- Peptide aptamers: tools for biology and drug discovery.
- Inhibition of complement C3 and fibrinogen interaction: a potential novel therapeutic target to reduce cardiovascular disease in diabetes.
- Adhiron: a stable and versatile peptide display scaffold for molecular recognition applications.
- Sensitive affimer and antibody based impedimetric label-free assays for C-reactive protein.
- Structure-function studies of an engineered scaffold protein derived from Stefin A. II: Development and applications of the SQT variant.
- Beyond Antibodies as Binding Partners: The Role of Antibody Mimetics in Bioanalysis
- Structure-function studies of an engineered scaffold protein derived from stefin A. I: Development of the SQM variant
- Label-free sub-picomolar protein detection with field-effect transistors.
- Peptide Aptamers in Label-Free Protein Detection: 1. Characterization of the Immobilized Scaffold
- Highly specific label-free protein detection from lysed cells using internally referenced microcantilever sensors.
- Electrical protein detection in cell lysates using high-density peptide-aptamer microarrays.
- Surface-immobilized peptide aptamers as probe molecules for protein detection.
- Peptide aptamers in label-free protein detection: 2. Chemical optimization and detection of distinct protein isoforms.
- Design and validation of a neutral protein scaffold for the presentation of peptide aptamers.
- Comparative diagnostic performance of the new chromatographic Affimer®-based rapid antigen detection against SARS-CoV-2 and other standard antigen tests for COVID-19 in a clinical setting.